News and Annoucements

All announcements, news, seminars and conferences below:

New Rates as of Oct 1st, 2016

Please note that all facilities in the CCIC (MS&P, NMR, X-Ray) will have a rate change effective October 1, 2016.

Please refer to the individual rate pages for the new rates:

TopSpin NMR Software is now free!

Bruker announced at the 57th ENC held in Pittsburgh in April 2016 that they will now provide the latest version of TopSpin processing software for free for academic use. TopSpin is used on all of the instruments in the CCIC NMR Facility and offers many useful tools for analysis and visualization of data acquired at the facility. For details and download, please see Bruker's Announcement.

Proteomics Summer Workshop 2015

DATES: Monday, 27 - Tuesday, July 28 2015
LOCATION: Biomedical Research Tower (BRT), Room 115 (460 W. 12th Ave, Columbus OH 43210)
REGISTRATION: Registration in now CLOSED

The Proteomics Summer Workshop is organized by the CCIC Mass Spectrometry and Proteomics (MSP) Facility. Our goal is to provide/refresh information about how present day mass spectrometry can help you in your proteomics related research. The workshop is mostly application oriented and will cover the following topics: sample preparation (protein purification, separation/fractionation), HPLC-MS/MS techniques, a brief summary of LTQ, Orbitrap and FT-ICR instrumentation, peptide sequencing, bottom up/top down proteomics, post translational modification (PTMs), and MALDI imaging. This Workshop will also give us an opportunity to get to know each other better, to discuss your own research and needs and initiate scientifically valuable collaborations.

This workshop is offered free of charge to everybody, including OSU researchers and the local community. The tentative schedule is shown below. The pdf copies of the presentations will be made available on the website prior to the class. All lecture notes should be available by Friday, July 24th. Please sign-up so that we know how many of you to expect. You are welcome to attend for any part of the 2 days. Hope to see you there!

 Workshop Schedule

Click on the links below to download a PDF of the presentations for each session.

Time
Monday, 7/27
Tuesday, 7/28
9-10:20am Introduction to Proteomics
(Mike)
Proteomics - (PTMs)
(Liwen)

Proteomics - MALDI Image
(Nan)
10:35-12:00pm Sample Prep I (Protein Purification)
(Cindy)
Proteomics - (Quantitation)
(Jeremy)
12-1pm Lunch Break Lunch Break
1-2:30pm Lab visit (Group 1) Lab visit (Group 2)
2:40-4pm Sample Prep II - (Protein Separation, Modification)
(Cindy)
New Instruments and Services
(Liwen)

Open Discussion/Users Presentations

Contact Persons:

Dr. Liwen Zhang (zhang.287@osu.edu)
Research Scientist
Technical Director for Proteomics

Dr. Cindy James (james.456@osu.edu)
Senior Research Associate

Special Seminar June 9th on ultrahigh resolution Fourier Transform Ion-Cyclotron Mass Spectrometry (FT-ICR)!

We are pleased to announce that Professor Eugene Nikolaev from the Institute for Energy Problems of Chemical Physics Russian Academy of Sciences will present a special seminar June 9th at 11:45 am in CBEC 130.

“Recent Developments in FT-ICR instrumentation, data processing and application”.

Professor Nikolaev is an internationally recognized scientist who significantly contributed to the development and improvement of FT-ICR mass spectrometry broadening its use for top down proteomics, metabolomics, environmental issues, etc. Please attend if you can.

CCIC NMR getting involved in major metabolomics initiative by NIH

NIH has funded the integrated metabolomics center SECIM in which the Bruschweiler Lab is an active participant. Our contribution to SECIM and CCIC-NMR is making web server and software tools available for the (semi-)automated analysis of metabolomic mixtures by NMR, see http://spin.ccic.ohio-state.edu/.

Rafael Brüschweiler assumes NMR Executive Director position for CCIC

Rafael Brüschweiler joined OSU as Ohio Research Scholar in August 2013 with joint appointments at the Department of Chemistry and Biochemistry and at the College of Medicine. He received his Ph.D. in 1991 in Physical Chemistry from ETH Zurich, Switzerland, before doing a postdoc at the Department of Molecular Biology at the Scripps Research Institute, La Jolla. In 2004, he joined the Florida State University, Tallahassee, as full professor and the National High Magnetic Field Laboratory as Associate Director for Biophysics. His lab's research is highly cross-disciplinary in the area of biophysical chemistry as well as analytical chemistry. It focuses on the understanding of the role of dynamics and thermodynamics of proteins properties for their function and on the analysis of complex biological mixtures in the context of metabolomics. The main research tools are high-field nuclear magnetic resonance (NMR) and high-performance computation, which includes the development of new and improved techniques. Biological systems studied in the lab include the proteins p53/MDM2, sodium-calcium exchanger NCX, Cu2+-ATPase, ubiquitin, and the enzymes arginine kinase and glucokinase. Metabolic studies are conducted on drosophila, E. coli, yeast, and cancer cell lines in combination with isotope labeling, such as carbon-13.

Wysocki is new Ohio Eminent Scholar

From: http://oncampus.osu.edu/2012/06/wysocki-is-new-ohio-eminent-scholar/

The latest Ohio Eminent Scholar in Macromolecular Structure and Function connects basic research with medicine.

In addition to becoming a professor in the Departments of Chemistry and Biochemistry, Vicki Wysocki also will direct the Campus Chemical Instrumentation Center, which provides state-of-the-art research facilities for the entire campus in three areas: Nuclear magnetic resonance, mass spectrometry and proteomics.

She begins her appointment on Aug. 1.

Wysocki, currently professor and chair of the Department of Chemistry and Biochemistry at the University of Arizona, specializes in finding new ways to study molecules that are critical to health and medicine.

For instance, she and her team use a technique called “surface-induced dissociation,” which involves smashing molecules against specialized surfaces and then examining the broken pieces to see how they might fit together. Ultimately, the work could lead to new understanding of conditions such as high blood pressure, stiffening of the arteries and chronic obstructive pulmonary disease, among many others.

As to why she chose Ohio State, Wysocki said that the university is clearly on the upswing, with new faculty hires, the expansion of the Wexner Medical Center and the merger of the Departments of Chemistry and Biochemistry. President Gordon Gee’s notion of “One University” also resonated with her.

“Some universities feel like silos,” she said. “OSU feels like a full campus.”

Wysocki’s husband, Ron, also a PhD chemist, will become the new program director in the Chemistry and Biochemistry Undergraduate Office.

The Ohio Eminent Scholars Program was created by the Ohio General Assembly and is administered by the Ohio Board of Regents. Its goal is to enhance the national eminence of selected outstanding academic programs at Ohio universities by attracting nationally recognized scholars.

CCIC hires NMR associate director

Dr. Tapas Mal has assumed the position of associate director, Campus Chemical Instrument Center (CCIC)/Nuclear Magnetic Resonance (NMR). Prior to joining the university, Dr. Mal served as the manager for the NMR facility at Pfizer Pharmaceutical Corporation.Dr. Mal brings to this position extensive technical and managerial expertise in NMR spectroscopy.

His work spans a broad range of applications including biomolecular structure molecule analysis, drug-protein interactions, and metabolomics.

The CCIC provides state-of-the-art research facilities for the campus in three areas: Nuclear Magnetic Resonance, Mass Spectrometry, and Proteomics.