Rafael Brüschweiler assumes NMR Executive Director position for CCIC

Rafael Brüschweiler joined OSU as Ohio Research Scholar in August 2013 with joint appointments at the Department of Chemistry and Biochemistry and at the College of Medicine. He received his Ph.D. in 1991 in Physical Chemistry from ETH Zurich, Switzerland, before doing a postdoc at the Department of Molecular Biology at the Scripps Research Institute, La Jolla. In 2004, he joined the Florida State University, Tallahassee, as full professor and the National High Magnetic Field Laboratory as Associate Director for Biophysics. His lab's research is highly cross-disciplinary in the area of biophysical chemistry as well as analytical chemistry. It focuses on the understanding of the role of dynamics and thermodynamics of proteins properties for their function and on the analysis of complex biological mixtures in the context of metabolomics. The main research tools are high-field nuclear magnetic resonance (NMR) and high-performance computation, which includes the development of new and improved techniques. Biological systems studied in the lab include the proteins p53/MDM2, sodium-calcium exchanger NCX, Cu2+-ATPase, ubiquitin, and the enzymes arginine kinase and glucokinase. Metabolic studies are conducted on drosophila, E. coli, yeast, and cancer cell lines in combination with isotope labeling, such as carbon-13.